Enfermedad de Castleman multicéntrica en sida. Su relación con el VHH-8 o virus herpes asociadoal sarcoma de Kaposi. Estudio de dos casos / Multicenter Castleman disease in AIDS. Its relationship with HHV-8 or hespes virus associated to Kaposi's sarcoma. Study of two cases

La enfermedad de Castleman está considerada como un cuadro linfadenopático reactivo con dos formas clínicas: una localizada, frecuente en pacientes inmunocompetentes, y otra multicéntrica, más característica en los enfermos inmunodeprimidos. Se presentan dos casos de enfermedad de Castleman multicéntrica en pacientes VIH positivos con sarcoma de Kaposi. Ambos pacientes muestran adenopatías múltiples, hepatomegalia y síntomas B al diagnóstico. Uno de ellos presenta respuesta favorable al tratamiento quimioterápico y el otro fallece. Se realiza una revisión del concepto de enfermedad de Castleman multicéntrica, así como su relación patogénica con el virus herpes humano-8

Castleman disease is considered a reactive lymphadenopathic picture with two clinical forms: one localized, frequent in immunocompetent patients and another multicenter one that is more characteristic in immunodepressed patients. Two cases of Castleman disease multicenter in HIV positive patients with Kaposi's sarcoma are presented. Both patients have multiple adenopathies, hepatomegaly and symptoms B on diagnosis. One of them had a favorable response to chemotherapy treatment and another died. A review of the concept of multicenter Castleman disease and its pathogenic relationship to human herpes virus 8 (HHV-8) is done

[Multicenter Castleman disease in AIDS. Its relationship with HHV-8 or herpes virus associated to Kaposi's sarcoma. Study of two cases]. / Enfermedad de Castleman multicéntrica en sida. Su relación con el VHH-8 o virus herpes asociado al sarcoma de Kaposi. Estudio de dos casos.

Castleman disease is considered a reactive lymphadenopathic picture with two clinical forms: one localized, frequent in immunocompetent patients and another multicenter one that is more characteristic in immunodepressed patients. Two cases of Castleman disease multicenter in HIV positive patients with Kaposi's sarcoma are presented. Both patients have multiple adenopathies, hepatomegaly and symptoms B on diagnosis. One of them had a favorable response to chemotherapy treatment and another died. A review of the concept of multicenter Castleman disease and its pathogenic relationship to human herpes virus 8 (HHV-8) is done.

[ORL manifestations of Wegener's disease]. / Manifestaciones ORL de la enfermedad de Wegener.

Wegener's disease is characterized by necrotizing granulomatous vasculitis. The localized form involves the upper and lower respiratory tract, in the generalized form, the kidneys are also involved. In this paper, three cases of Wegener granulomatosis with otorhinolaryngological symptoms are reported. Frequently the presentation of this disease occurs in the ears, nose and throat, we think that the knowledge of this granulomatosis by the otorhinolaryngologist is necessary.

[Bladder paraganglioma. Apropos of a case]. / Paraganglioma vesical. A propósito de un caso.

A case of non-secreting bladder paraganglioma whose clinical manifestation was that of painless hematuria is described herein. Treatment was by partial cystectomy.